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Biocon receives positive efficacy data with its novel monoclonal antibody Itolizumab

16 Jan 2012 Evaluate

Biocon, Asia's premier biotechnology company has received positive results from its double blind, placebo controlled, Phase 3, TREAT-PLAQ study with Itolizumab in chronic plaque psoriasis.

Itolizumab, the first humanized anti CD-6 monoclonal antibody, successfully met the pre-specified primary endpoint of significant improvement in PASI-75 (Psoriasis Area and Severity Index) score after 12 weeks of treatment in patients with moderate to severe psoriasis compared to placebo. It also met multiple secondary endpoints after 12 and 28 weeks of treatment.

This 52 week study conducted in India, had a 12 week placebo controlled phase, 16 week consolidation and 24 week randomized withdrawal phase. It enrolled over 200 patients across placebo and two active treatment regimens. The company plans on presenting the safety and efficacy data from the entire 52 week study at an upcoming scientific meeting.

Biocon is Asia’s leading R&D based Biotechnology Company. It produces anti-diabetic agents like Acarbose, Pioglitazone, Repaglinides and Rosiglitazone. In the biological segment it produces Insulin, Erythropoietin (EPO), Filgrastim (GCSF), Streptokinase and Monoclonal Antibodies. The drug major also produces mycophenolate mofetil, sirolimus and tacrolimus.

Biocon Share Price

380.55 -2.05 (-0.54%)
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