Lupin rises as its JV completes global Phase III clinical trial of Etanercept biosimilar

Lupin Ltd. | Pharmaceuticals & Drugs | Healthcare | BSE: 500257 | NSE: LUPIN

09 Feb 2018 Evaluate

Lupin is currently trading at Rs. 820.95, up by 6.50 points or 0.80% from its previous closing of Rs. 814.45 on the BSE.

The scrip opened at Rs. 805.00 and has touched a high and low of Rs. 829.00 and Rs. 800.00 respectively. So far 128890 shares were traded on the counter.

The BSE group 'A' stock of face value Rs. 2 has touched a 52 week high of Rs. 1520.00 on 09-Feb-2017 and a 52 week low of Rs. 782.10 on 07-Feb-2018.

Last one week high and low of the scrip stood at Rs. 859.50 and Rs. 782.10 respectively. The current market cap of the company is Rs. 37061.93 crore.

The promoters holding in the company stood at 47.02%, while Institutions and Non-Institutions held 37.64% and 15.35% respectively.

Lupin’s joint venture (JV) YL Biologics (YLB) has successfully completed global Phase III clinical trial of its investigational Etanercept biosimilar (YLB113). The Phase III study of YLB113 was a multinational randomized double-blind controlled trial of 52 weeks duration which included more than 500 patients with rheumatoid arthritis (RA) in 11 countries. It compared YLB113’s efficacy and safety directly against Enbrel (of Amgen/Pfizer) which has a global market of $11 billion (IQVIA MAT Q3 2017), and is a widely successful biologic agent globally used for the treatment of multiple autoimmune disorders including RA. YLB is a joint venture between the company and Yoshindo in Japan.

The primary endpoint was an equivalent improvement in the rheumatoid arthritis, as measured by American College of Rheumatology 20 (ACR20) response rate. The ACR20 response rate of YLB113 has been found to be within a pre-defined equivalence margin that is expected by most advanced regulatory agencies for marketing authorization. In addition, safety and immunogenicity (antibody formation) of YLB113 was also found to be similar to Enbrel indicating therapeutic equivalence.

Lupin is an innovation led transnational pharmaceutical company developing and delivering a wide range of branded & generic formulations, biotechnology products and APIs globally. The Company is a significant player in the Cardiovascular, Diabetology, Asthma, Pediatric, CNS, GI, Anti-Infective and NSAID space and holds global leadership position in the Anti-TB segment.

Lupin Share Price

2303.70 -7.20 (-0.31%)

30-Apr-2026 16:59 View Price Chart

Peers

Company Name	CMP
Sun Pharma Inds.	1808.20
Dr. Reddys Lab	1322.95
Cipla	1309.90
Zydus Lifesciences	891.65
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