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Glenmark Pharmaceuticals to initiate clinical study for GBR 1342

16 May 2017 Evaluate

Glenmark Pharmaceuticals, a global pharmaceutical company will initiate clinical study for GBR 1342. The US Food and Drug Administration (USFDA) cleared the company’s Investigational New Drug (IND) application to initiate a Phase 1 study of GBR 1342, a humanized, bispecific monoclonal antibody (bsAb) being studied for the treatment of multiple myeloma in patients who have received prior therapies.

GBR 1342 is designed to activate the patient’s immune system by redirecting immune cells towards tumor tissue, which may lead to targeted destruction of tumors. It is based on Glenmark’s proprietary BEAT (Bispecific Engagement by Antibodies based on the T cell receptor) technology platform.

The first-in-human Phase 1 study of GBR 1342 will enroll subjects with multiple myeloma who have exhausted available therapies.


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