Alembic Pharmaceuticals’ step down wholly owned subsidiary -- Rhizen has received approval from US Food and Drug Administration (USFDA) for its Investigational New Drug (IND) application to study its oral DHODH inhibitor for SARS-CoV-2 infection. The initial study shall evaluate single ascending doses of RP7214 in healthy volunteers and that dosing is expected to commence in early December 2020.
Dihydroorotate dehydrogenase (DHOHD) is a key enzyme involved in pyrimidine biosynthesis in the cell. RP7214 is potentially a best-in-class selective DHODH inhibitor that has shown potent inhibition of Covid19 viral replication.
Alembic Pharmaceuticals, a vertically integrated research and development pharmaceutical company, has been at the forefront of Healthcare since 1907.
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